SCHEMBL108692

SCHEMBL108692

C=CC(=O)OC[Si](C)(OC)OC

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.45
ALDH1A1 P00352 5/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.43
THRB P10828 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27853675 0.87 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6037079 0.85 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL107384 0.83 TSHR (0.45) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3957027 0.83 HCAR2 (0.40)
SCHEMBL397010 0.82 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL106615 0.81 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL600138 0.80 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2403942 0.80 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9411504 0.80 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16536758 0.80 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264813-A Photo-curing high-temperature-resistant optical fiber coating and preparation method thereof 普利技术潜江有限公司 2025-01-07 CN claimed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
EP-3328958-B1 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2022-10-05 EP claimed
EP-4035649-A1 DENTAL ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2022-08-03 EP claimed
EP-3328958-A2 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS fischerwerke GmbH & Co. KG (DE) 2018-06-06 EP claimed
EP-3268411-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP & Holding GmbH (DE) 2018-01-17 EP claimed
WO-2016141547-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP Holding GmbH (DE) 2016-09-15 WO claimed
US-8865837-B2 Organosilicon compounds, production processes thereof, pressure-sensitive adhesive compositions containing the organosilicon compounds, self-adhesive polarizers and liquid crystal displays SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-21 US claimed
US-8431649-B2 Organosilicon compounds, production processes thereof, pressure-sensitive adhesive compositions containing the organosilicon compounds, self-adhesive polarizers and liquid crystal displays SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-30 US claimed
US-20130066014-A1 ORGANOSILICON COMPOUNDS, PRODUCTION PROCESSES THEREOF, PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS CONTAINING THE ORGANOSILICON COMPOUNDS, SELF-ADHESIVE POLARIZERS AND LIQUID CRYSTAL DISPLAYS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-03-14 US claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
EP-4727982-A1 PRIMER COMPOSITION, ADHESIVE SYSTEM, AND RELATED PROCESSES 3M Innovative Properties Company (US) 2026-04-22 EP disclosed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
EP-4174097-B1 ACRYLIC EMULSION-BASED POLYMER AND PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS COMPRISING THE SAME NITTO BELGIUM NV (BE) 2026-03-18 EP disclosed
US-5025049-A Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-18 US disclosed
US-5021266-A Silicon based protective coating SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-04 US disclosed
US-4960809-A CURABLE MIXTURE OF ALKOXYSILYL-CONTAINING ADDITION COPOLYMER AND AN AMIDATED POLYMER OF AN AMINE-CONTAINING ALKOXYSILANE AND SILYLATING AGENT; ADHESION TO SILICONE OVERCOATINGS AND POLYCARBONATE SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-02 US disclosed
EP-0373659-A2 Method for the preparation of polyorganosiloxane and radiation-curable composition Dow Corning Toray Silicone Company Ltd. (JP) 1990-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885TP53 4663/4885
US-20130066014-A1 ORGANOSILICON COMPOUNDS, PRODUCTION PROCESSES THEREOF, PRESSURE-SENSITIVE ADHESIVE COMPOSITIONS CONTAINING THE ORGANOSILICON COMPOUNDS, SELF-ADHESIVE POLARIZERS AND LIQUID CRYSTAL DISPLAYS L1CAM, CDH1, CCND1 TSHR 4334/4885ALDH1A1 1658/4885TP53 3163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.