Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871169 | 0.85 | KDM4B (0.34) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL10521863 | 0.80 | LSS (0.50) | NOS1NOS2LTA4HROCK1ROCK2 | |
| SCHEMBL10518366 | 0.76 | MAPT (0.53) | NOS1NOS2LTA4HROCK1ROCK2 | |
| SCHEMBL10519858 | 0.75 | TSHR (0.43) | NOS1NOS2LTA4HROCK1ROCK2 | |
| SCHEMBL10868925 | 0.73 | ALDH1A1 (0.36) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL10521093 | 0.72 | LSS (0.47) | NOS1NOS2LTA4HATP4AATP4B | |
| SCHEMBL10869929 | 0.69 | ATP4A (0.35) | LTA4HATP4AATP4BROCK1ROCK2 | |
| SCHEMBL12495744 | 0.67 | ATP4A (0.67) | LTA4HATP4AATP4BCYP3A4MEN1 | |
| SCHEMBL11197263 | 0.67 | NPC1 (0.48) | NOS1NOS2PPARACA12CA1 | |
| SCHEMBL10520147 | 0.66 | LSS (0.41) | ATP4AATP4BROCK1ROCK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |