Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909792 | 0.89 | CTSB (0.55) | CTSKHTRA1CTSB | |
| SCHEMBL11006634 | 0.87 | REN (0.49) | CTSKCTSLPSMB5CTSBCTSS | |
| SCHEMBL7938093 | 0.86 | CAPN1 (0.60) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL7274809 | 0.84 | CAPN1 (0.60) | CTSKCAPN1HTRA1CTSLCTSB | |
| SCHEMBL11013588 | 0.82 | TACR1 (0.61) | CTSKCTSLCTSBCTSS | |
| SCHEMBL10979007 | 0.81 | MME (0.54) | CTSKCAPN1HTRA1CTSLCTSB | |
| SCHEMBL10977845 | 0.81 | MME (0.54) | CTSKCAPN1HTRA1CTSLCTSB | |
| SCHEMBL10636524 | 0.80 | CTSK (0.54) | CTSKCAPN1HTRA1CTSLPSMB5 | |
| SCHEMBL10636541 | 0.80 | CTSL (0.59) | CAPN1CTSLPSMB5CTSBCTSS | |
| SCHEMBL19190188 | 0.80 | MMP3 (0.49) | CTSKCAPN1HTRA1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |