Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872706 | 0.82 | RAB9A (0.56) | SMN1; SMN2KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10289219 | 0.80 | HDAC3 (0.78) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL5637555 | 0.80 | NR4A1 (0.56) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL25870996 | 0.78 | NR4A1 (0.66) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL16233172 | 0.78 | SLC6A5 (0.55) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL863916 | 0.78 | ALDH1A1 (0.88) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL748869 | 0.78 | SPHK2 (0.81) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL13624261 | 0.78 | LTA4H (0.54) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28761131 | 0.77 | ALDH1A1 (0.66) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL1222408 | 0.77 | ITGB3 (0.73) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199042-A1 | Procainamide assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |