SCHEMBL1087503

SCHEMBL1087503

COc1cc(Cl)c(CO)cc1NC(=O)C(C)C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
HPGD P15428 2/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 4/20 0.42
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
STAT3 P40763 1/20 0.42
MAPK1 P28482 1/20 0.41
LMNA P02545 4/20 0.41
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8930615 0.85 SMN1; SMN2 (0.57) ALDH1A1HPGDGAAHTTSMN1; SMN2
SCHEMBL8930613 0.76 CRHBP (0.64) ALDH1A1GAASMN1; SMN2MEN1KMT2A
SCHEMBL26816560 0.72 HTT (0.58) ALDH1A1HPGDGAAHTTSMN1; SMN2
SCHEMBL26816572 0.72 ALDH1A1 (0.61) ALDH1A1HPGDHTTSMN1; SMN2MEN1
SCHEMBL8930803 0.71 LPAR1 (0.66) ALDH1A1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL3396291 0.70 PDE4A (0.57) MEN1KMT2AMAPT
SCHEMBL21851950 0.70 SMN1; SMN2 (0.58) ALDH1A1HPGDGAAHTTSMN1; SMN2
SCHEMBL10049712 0.69 LPAR1 (0.39) ALDH1A1KMT2AMAPTLMNA
SCHEMBL8930775 0.69 POLB (0.58) ALDH1A1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL8962002 0.69 L3MBTL1 (0.53) ALDH1A1HPGDGAAHTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9612532-B2 Photosensitive coloring composition, color filter, method for producing color filter, organic el liquid crystal display device, and color filter forming kit FUJIFILM CORPORATION (JP) 2017-04-04 US disclosed
US-20160139505-A1 PHOTOSENSITIVE COLORING COMPOSITION, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, ORGANIC EL LIQUID CRYSTAL DISPLAY DEVICE, AND COLOR FILTER FORMING KIT FUJIFILM CORPORATION (JP) 2016-05-19 US disclosed
US-8465553-B2 Pigment dispersion composition, colored curable composition, color filter for solid-state image sensor and method of producing the same, and solid-state image sensor FUJIFILM CORPORATION (JP) 2013-06-18 US disclosed
US-20120286145-A1 PIGMENT DISPERSION COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR SOLID-STATE IMAGE SENSOR AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2012-11-15 US disclosed
US-8152863-B2 Pigment dispersion composition, red colored composition, colored curable composition, color filter for a solid state imaging device and method for producing the same, and solid state imaging device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20110294050-A1 PIGMENT DISPERSION COMPOSITION, RED COLORED COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR A SOLID STATE IMAGING DEVICE AND METHOD FOR PRODUCING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-12-01 US disclosed