SCHEMBL1088784

SCHEMBL1088784

[CH]C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.44
GRIN3B O60391 5/20 0.44
GRIN1 Q05586 5/20 0.44
GRIN2A Q12879 5/20 0.44
GRIN2B Q13224 5/20 0.44
GRIN2C Q14957 5/20 0.44
GRIN3A Q8TCU5 5/20 0.44
LMNA P02545 2/20 0.44
SLC22A2 O15244 2/20 0.44
SLC47A1 Q96FL8 2/20 0.44
SLC22A1 O15245 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
STAT6 P42226 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
POLB P06746 1/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963771 0.67 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2746527 0.67 ALDH1A1 (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9296018 0.65
SCHEMBL1199716 0.62 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10723906 0.62 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24236 0.62
SCHEMBL23333268 0.61 PKM (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2972540 0.61 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL179945 0.61 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Amantadine SCHEMBL21310017 0.61 GRIN1 (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110683926-B Preparation method of carboxylic acid aryl ester compound 北京大学深圳研究生院 2022-11-04 CN claimed
US-20080255076-A1 Steroid-Derived Pharmaceutical Compositions JADOLABS GMBH (DE) 2008-10-16 US claimed
US-20080090913-A1 Sphingolipid-Derived Phamaceutical Compositions JADO TECHNOLOGIES GMBH (DE) 2008-04-17 US claimed
US-20070265278-A1 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS AVENTIS PHARMACEUTICALS INC. (US) 2007-11-15 US claimed
EP-1844011-A1 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS Aventis Pharmaceuticals Inc. (US) 2007-10-17 EP claimed
EP-1763342-A2 SPHINGOLIPIDS AGAINST PATHOLOGICAL PROCESSES IN LIPID RAFTS Jadolabs Gmbh (DE) 2007-03-21 EP claimed
WO-2006081343-A1 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS AVENTIS PHARMACEUTICALS INC. (US) 2006-08-03 WO claimed
EP-1558654-A4 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-04-05 EP claimed
WO-2006002909-A2 SPHINGOLIPIDS AGAINST PATHOLOGICAL PROCESSES IN LIPID RAFTS JADOLABS GMBH (DE) 2006-01-12 WO claimed
EP-1558654-A2 NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF Fujifilm Electronic Materials USA, Inc. (US) 2005-08-03 EP claimed
US-6916543-B2 Copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. (US) 2005-07-12 US claimed
US-20040137362-A1 Novel copolymer, photoresist compositions thereof and deep UV bilayer system thereof ARCH SPECIALTY CHEMICALS, INC. 2004-07-15 US claimed
WO-2004040371-A2 NOVEL COPOLYMER AND PHOTORESIST COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2004-05-13 WO claimed
US-6309796-B1 PHOTORESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-10-30 US claimed
EP-0954526-A2 SERINE PROTEASE INHIBITORS CORTECH, INC. (US) 1999-11-10 EP claimed
WO-1998024806-A2 SUBSTITUTED OXADIAZOLE, THIADIAZOLE AND TRIAZOLE SERINE PROTEASE INHIBITORS CORTECH, INC. (US) 1998-06-11 WO claimed
US-20240239820-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION INCLUDING THE SAME AND PATTERN FORMING METHOD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-18 US disclosed
US-20240231228-A1 RESIST COMPOSITION AND METHOD OF FORMING PATTERN BY USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-11 US disclosed
US-20020058205-A1 High molecular weight silicone compounds, resist compositions, and patterning method NAKASHIMA MUTSUO (JP) 2002-05-16 US disclosed
US-6309796-B1 PHOTORESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265278-A1 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS PTGDR2, PTGDR, CYSLTR2 GRIN2D 900/4885GRIN3B 1791/4885GRIN1 3120/4885
US-20080255076-A1 Steroid-Derived Pharmaceutical Compositions CYP11A1, CYP11B2, CYP11B1 GRIN2D 1344/4885GRIN3B 377/4885GRIN1 613/4885
US-20240239820-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION INCLUDING THE SAME AND PATTERN FORMING METHOD USING THE SAME RBM14, PRMT1, RBM15 GRIN2D 1509/4885GRIN3B 1387/4885GRIN1 228/4885
US-20080090913-A1 Sphingolipid-Derived Phamaceutical Compositions SGMS1, SGMS2, SMPD2 GRIN2D 3040/4885GRIN3B 2084/4885GRIN1 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.