Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545381 | 0.82 | ELANE (0.45) | POLBELANEATML3MBTL1NPC1 | |
| SCHEMBL10584779 | 0.82 | HPGD (0.46) | ELANEATML3MBTL1NPC1RAB9A | |
| SCHEMBL666155 | 0.81 | POLB (0.47) | POLBELANEATML3MBTL1NPC1 | |
| SCHEMBL237447 | 0.79 | CES2 (0.50) | ELANEATML3MBTL1NPC1RAB9A | |
| SCHEMBL5312067 | 0.77 | SLC7A5 (0.50) | LMNAMEN1ALDH1A1KMT2AUSP2 | |
| SCHEMBL58882 | 0.76 | TDP1 (0.44) | ELANEATML3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8069670 | 0.76 | MAPT (0.46) | ELANEATML3MBTL1ALDH1A1GAA | |
| SCHEMBL1088831 | 0.76 | CES2 (0.53) | ELANEATML3MBTL1MEN1ALDH1A1 | |
| SCHEMBL6654150 | 0.75 | ALDH1A1 (0.55) | ATML3MBTL1NPC1RAB9ALMNA | |
| Phenol SCHEMBL9251256 | 0.75 | MIF (0.45) | POLBELANEATML3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033125-A | A kind of Ai Le replaces the preparation method of Buddhist nun | 湖南博奥德生物医药技术开发有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-110234623-B | Solution containing dialkylzinc and dialkylzinc partial hydrolysate, and method for producing zinc oxide thin film using same | 东曹精细化工株式会社 | 2023-04-18 | — | — | CN | disclosed |
| US-8153839-B2 | Method for synthesis of keto acids or amino acids by hydration of acetylene compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-1932824-A1 | METHOD FOR SYNTHESIS OF KETO ACID OR AMINO ACID BY HYDRATION OF ACETHYLENE COMPOUND | Japan Science and Technology Agency (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-5523459-A | OXIDIZING ALPHA-HYDROXYCARBOXYLIC ACID ESTER WITH MOLECULAR OXYGEN IN GASEOUS PHASE IN PRESENCE OF COPPER PHOSPHATE | UBE INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0673914-A2 | Preparation of alpha-keto acid ester | UBE INDUSTRIES, LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0310034-A2 | Process for production of L-phenylalanine lower alkyl esters | KURARAY CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216044-A1 | METHOD FOR SYNTHESIS OF KETO ACIDS OR AMINO ACIDS BY HYDRATION OF ACETYLENE COMPOUND | AADAT, BCAT2, BCAT1 | POLB 3155/4885ELANE 956/4885ATM 1558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.