Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627091 | 0.87 | LMNA (0.56) | SMN1; SMN2ALDH1A1MAPK1HSD17B10ADORA2A | |
| SCHEMBL7046067 | 0.85 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL1108964 | 0.80 | TYMS (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28209330 | 0.80 | IRAK4 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL11524230 | 0.80 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL29006649 | 0.79 | ABL1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL204726 | 0.78 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9860818 | 0.77 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL10808699 | 0.77 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL30166994 | 0.77 | HTR6 (0.42) | SMN1; SMN2ALDH1A1MAPK1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202568-A1 | Anthelmintic compositions | SYNTEX (U.S.A.) INC. (US) | 1986-11-26 | — | — | EP | claimed |