Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 9/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219230 | 0.90 | ABL1 (0.47) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| Oxfendazole SCHEMBL29409244 | 0.88 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2ADORA2ALMNA | |
| Oxfendazole SCHEMBL44121 | 0.88 | LMNA (0.55) | NPC1RAB9ASMN1; SMN2ADORA2ALMNA | |
| Oxfendazole SCHEMBL27586080 | 0.87 | LMNA (0.54) | NPC1RAB9ASMN1; SMN2ADORA2ALMNA | |
| SCHEMBL8411241 | 0.84 | ALDH1A1 (0.48) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| Oxfendazole SCHEMBL28641495 | 0.83 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2ADORA2ALMNA | |
| SCHEMBL11532983 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL10902961 | 0.82 | NPC1 (0.42) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL11259731 | 0.81 | MAPT (0.36) | NPC1RAB9APKMSMN1; SMN2MAOB | |
| SCHEMBL11589337 | 0.81 | SMN1; SMN2 (0.42) | NPC1RAB9APKMSMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060810-B1 | ANTHELMINTICS | CIBA-GEIGY AG (CH) | 1984-10-17 | — | — | EP | claimed |
| US-4076827-A | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | claimed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| US-20220008542-A1 | ANTI-PROTOZOAL COMPOUNDS AND USES THEREOF | UNIV AUBURN (US) | 2022-01-13 | — | — | US | disclosed |
| US-11160867-B2 | Anti-protozoal compounds and uses thereof | AUBURN UNIVERSITY (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210277221-A1 | RESIN COMPOSITION, LAMINATE, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE FOR MOUNTING SEMICONDUCTOR WITH RESIN COMPOSITION LAYER AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-09-09 | — | — | US | disclosed |
| EP-3786200-A1 | RESIN COMPOSITION, LAMINATE, RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR WAFER, SUBSTRATE FOR MOUNTING RESIN COMPOSITION LAYER-ATTACHED SEMICONDUCTOR, AND SEMICONDUCTOR DEVICE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-03-03 | — | — | EP | disclosed |
| CN-112004845-A | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer, and semiconductor device | 三菱瓦斯化学株式会社 | 2020-11-27 | — | — | CN | disclosed |
| CN-110693830-A | Veterinary oxfendazole nano suspension and preparation method thereof | 华中农业大学 | 2020-01-17 | — | — | CN | disclosed |
| US-20180326072-A1 | ANTI-PROTOZOAL COMPOUNDS AND USES THEREOF | AUBURN UNIVERSITY | 2018-11-15 | — | — | US | disclosed |
| EP-0279343-B1 | COMBINATIONS OF ANTHELMINTICALLY ACTIVE AGENTS | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |
| EP-0146556-A4 | POTENTIATION OF ANTHELMINTICS. | COMMW SCIENT IND RES ORG (AU) | 1985-09-16 | — | — | EP | disclosed |
| EP-0146556-A1 | POTENTIATION OF ANTHELMINTICS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1985-07-03 | — | — | EP | disclosed |
| WO-1984004455-A1 | POTENTIATION OF ANTHELMINTICS | COMMW SCIENT IND RES ORG (AU) | 1984-11-22 | — | — | WO | disclosed |
| EP-0090368-A1 | Anthelmintic preparations | HOECHST UK LIMITED (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4331652-A | COPOLYMERIC MATRIX DERIVED FROM LACTIC ACID AND GLYCOLIC ACID | ELI LILLY AND COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4127664-A | BENZIMIDAZOLES | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4076827-A | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180326072-A1 | ANTI-PROTOZOAL COMPOUNDS AND USES THEREOF | PPIP5K2, PIGS, PGLS | NPC1 4439/4885RAB9A 2772/4885PKM 214/4885 |
| US-20220008542-A1 | ANTI-PROTOZOAL COMPOUNDS AND USES THEREOF | PPIP5K2, PIGS, PGLS | NPC1 4439/4885RAB9A 2772/4885PKM 214/4885 |
| US-11160867-B2 | Anti-protozoal compounds and uses thereof | PPIP5K2, PIGS, PGLS | NPC1 4439/4885RAB9A 2772/4885PKM 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.