Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10927176 | 0.85 | LTA4H (0.41) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL10928513 | 0.84 | HPGD (0.46) | ALDH1A1LMNATSHRMAPTTP53 | |
| SCHEMBL10925607 | 0.84 | CXCL8 (0.43) | ALDH1A1LMNATSHRSRD5A2MAPT | |
| SCHEMBL10923821 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRSRD5A2MAPT | |
| SCHEMBL10940123 | 0.82 | MAPT (0.48) | ALDH1A1MAPTTP53HPGDNPC1 | |
| SCHEMBL10925514 | 0.81 | TSHR (0.41) | ALDH1A1LMNATSHRSRD5A2MAPT | |
| SCHEMBL10926015 | 0.77 | NPC1 (0.63) | ALDH1A1LMNATSHRMAPTNPC1 | |
| SCHEMBL10928290 | 0.76 | AKR1C3 (0.40) | ALDH1A1LMNATSHRMAPTHPGD | |
| SCHEMBL10926631 | 0.73 | LMNA (0.39) | ALDH1A1LMNATSHRMAPTMEN1 | |
| SCHEMBL13429229 | 0.73 | SMPD1 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189080-A2 | (1,2,4-Oxadiazol-3-YL)-arylmethanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-30 | — | — | EP | disclosed |
| US-RE32154-E | FROM BENZO-THIETANE-2-SPIRO-2'(1,3'-DIZACCYCLOALKANE AND ALKYL HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | disclosed |
| US-4122263-A | REACTING A BENZOTHIETANE-2-SPIRO-2'(1',3'-DIAZACYCLOALKANE) WITH AN ALKYL HALIDE | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |