Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905761 | 0.87 | MAPT (0.41) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| Stearic Acid SCHEMBL9469601 | 0.74 | ALDH1A1 (0.56) | HDAC11ICMTALBSOAT2SOAT1 | |
| SCHEMBL10906603 | 0.74 | LTA4H (0.46) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| Hexanoate SCHEMBL28333349 | 0.74 | SOAT2 (0.57) | HDAC11ICMTALBSOAT2SOAT1 | |
| Stearic Acid SCHEMBL21838311 | 0.71 | HSD17B10 (0.61) | HDAC11SOAT2SOAT1EPHX1HTT | |
| Stearic Acid SCHEMBL9317212 | 0.71 | SOAT2 (0.52) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| Stearic Acid SCHEMBL9317244 | 0.71 | SOAT2 (0.52) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| Behenic Acid SCHEMBL9316968 | 0.71 | SOAT2 (0.52) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL8953270 | 0.71 | FFAR4 (0.53) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| Diphenylamine SCHEMBL21145171 | 0.70 | AKR1B1 (0.59) | HDAC11SOAT2SOAT1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |