Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.36 |
| ▸ | KDM4A | O75164 | 6/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704005 | 0.80 | TSHR (0.48) | TSHRALDH1A1KDM4CKDM5ALMNA | |
| SCHEMBL10903599 | 0.78 | LMNA (0.42) | TSHRALDH1A1LMNASLC22A6PHF8 | |
| SCHEMBL10906197 | 0.77 | KDM4C (0.38) | TSHRKDM4CKDM5ALMNASLC22A6 | |
| SCHEMBL10903614 | 0.76 | LMNA (0.40) | TSHRALDH1A1LMNASLC22A6PHF8 | |
| SCHEMBL10905757 | 0.74 | AKR1B1 (0.46) | TSHRALDH1A1KDM4CKDM5ASLC22A6 | |
| SCHEMBL4699893 | 0.74 | TSHR (0.47) | TSHRALDH1A1KDM4CKDM5ALMNA | |
| SCHEMBL10903601 | 0.74 | CAMK2A (0.44) | TSHRKDM4CKDM5ALMNASLC22A6 | |
| SCHEMBL10903627 | 0.74 | MEN1 (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL10907540 | 0.74 | ALDH1A1 (0.36) | TSHRALDH1A1KDM4CKDM5ALMNA | |
| SCHEMBL10907490 | 0.73 | LMNA (0.37) | TSHRALDH1A1LMNASLC22A6PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |