Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.36 |
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 10/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906139 | 0.91 | ALDH1A1 (0.39) | ALDH1A1ALDH2KDM4CKDM5ALMNA | |
| SCHEMBL10906197 | 0.81 | KDM4C (0.38) | KDM4CKDM5ALMNASLC22A6PHF8 | |
| SCHEMBL10906183 | 0.79 | MAPT (0.40) | ALDH1A1KDM4CKDM5ATSHR | |
| SCHEMBL10907490 | 0.78 | LMNA (0.37) | ALDH1A1LMNASLC22A6PHF8KDM2A | |
| SCHEMBL10906136 | 0.77 | LTA4H (0.45) | ALDH1A1 | |
| SCHEMBL10906181 | 0.76 | KDM4C (0.42) | KDM4CKDM5ALMNAPHF8KDM2A | |
| SCHEMBL10903599 | 0.75 | LMNA (0.42) | ALDH1A1LMNASLC22A6PHF8KDM2A | |
| SCHEMBL10903598 | 0.74 | TSHR (0.42) | ALDH1A1KDM4CKDM5APHF8KDM2A | |
| SCHEMBL10906138 | 0.74 | TSHR (0.45) | ALDH1A1KDM4CKDM5ALMNASLC22A6 | |
| SCHEMBL10903614 | 0.73 | LMNA (0.40) | ALDH1A1LMNASLC22A6PHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |