Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.33 |
| ▸ | KDM4A | O75164 | 11/20 | 0.33 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | KDM5C | P41229 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907540 | 0.91 | ALDH1A1 (0.36) | ALDH1A1ALDH2PHF8KDM2AKDM7A | |
| SCHEMBL10905398 | 0.72 | PHF8 (0.41) | ALDH1A1ALDH2PHF8KDM2AKDM7A | |
| SCHEMBL2806347 | 0.71 | PHF8 (0.48) | ALDH1A1ALDH2PHF8KDM2AKDM7A | |
| SCHEMBL10906197 | 0.71 | KDM4C (0.38) | PHF8KDM2AKDM7AKDM4CKDM4A | |
| SCHEMBL10906183 | 0.70 | MAPT (0.40) | ALDH1A1KDM4CKDM5AL3MBTL1 | |
| SCHEMBL10906181 | 0.69 | KDM4C (0.42) | PHF8KDM2AKDM7AKDM4CKDM4A | |
| SCHEMBL10907490 | 0.67 | LMNA (0.37) | ALDH1A1PHF8KDM2ALMNA | |
| SCHEMBL1281503 | 0.66 | PHF8 (0.48) | ALDH1A1ALDH2PHF8KDM2AKDM7A | |
| SCHEMBL103874 | 0.65 | — | — | |
| SCHEMBL718216 | 0.65 | KMT2A (0.56) | PHF8KDM2AKDM7AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4633014-A | ANTIARRHYTHMIA AGENTS | INSTITUT ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVIISKOI SSR | 1986-12-30 | — | — | US | disclosed |