Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | CD40 | P25942 | 3/20 | 0.42 |
| ▸ | CD40LG | P29965 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.40 |
| ▸ | FGF1 | P05230 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337486 | 0.93 | TIMP3 (0.47) | DEGS1CD40CD40LGENPP2KMT2A | |
| SCHEMBL10907652 | 0.90 | PRMT1 (0.42) | DEGS1CD40CD40LGENPP2KMT2A | |
| SCHEMBL10905547 | 0.88 | NPC1 (0.47) | KMT2AMEN1PRMT1TIMP3NPC1 | |
| SCHEMBL11427755 | 0.86 | CASP6 (0.48) | KMT2AMEN1PRMT1HPGDCASP6 | |
| SCHEMBL11338609 | 0.83 | PRMT1 (0.49) | DEGS1CD40CD40LGENPP2KMT2A | |
| SCHEMBL10907848 | 0.83 | DHODH (0.44) | KMT2AMEN1PRMT1TIMP3NPC1 | |
| SCHEMBL10905519 | 0.83 | LMNA (0.40) | ENPP2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10907712 | 0.82 | MPL (0.46) | DEGS1CD40CD40LGENPP2KMT2A | |
| SCHEMBL11437915 | 0.82 | CD40 (0.54) | CD40CD40LGKMT2AMEN1PRMT1 | |
| SCHEMBL10907905 | 0.81 | MPL (0.48) | CD40CD40LGENPP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599204-A | Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-08 | — | — | US | disclosed |