Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913894 | 0.93 | AHR (0.47) | POLBAHRKMT2AMEN1HPGD | |
| SCHEMBL10912457 | 0.81 | RAB9A (0.43) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10909622 | 0.78 | CA1 (0.55) | POLBKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL10912020 | 0.78 | ALDH1A1 (0.48) | POLBKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL7794720 | 0.77 | AHR (0.51) | POLBAHRKMT2AMEN1CASP1 | |
| SCHEMBL10913065 | 0.77 | MAPT (0.59) | MAPTL3MBTL1ALDH1A1SMN1; SMN2 | |
| Dimethylamine SCHEMBL10909871 | 0.76 | PDE10A (0.41) | POLBKMT2AMEN1HPGDMAPT | |
| SCHEMBL24182074 | 0.76 | AHR (0.50) | POLBAHRKMT2AMEN1CASP1 | |
| SCHEMBL21335854 | 0.76 | AHR (0.52) | POLBAHRKMT2AMEN1CASP1 | |
| Dimethylamine SCHEMBL10913743 | 0.75 | RAB9A (0.41) | POLBKMT2AMEN1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |