Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909799 | 0.93 | POLB (0.46) | AHRHPGDMAPTL3MBTL1POLB | |
| SCHEMBL10912078 | 0.80 | CA1 (0.44) | HPGDL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL7794720 | 0.79 | AHR (0.51) | AHRHPGDMAPTPOLBMAOA | |
| SCHEMBL24182074 | 0.78 | AHR (0.50) | AHRHPGDMAPTPOLBMAOA | |
| SCHEMBL21335854 | 0.77 | AHR (0.52) | AHRHPGDMAPTPOLBMAOA | |
| SCHEMBL10913396 | 0.77 | CA1 (0.57) | L3MBTL1POLBALDH1A1MAPK1MEN1 | |
| SCHEMBL10912534 | 0.77 | HPGD (0.49) | HPGDMAPTPOLBALDH1A1GAA | |
| SCHEMBL3774059 | 0.76 | ALDH1A1 (0.52) | HPGDMAPTL3MBTL1ALDH1A1CASP3 | |
| Dimethylamine SCHEMBL10914075 | 0.75 | RAB9A (0.43) | HPGDL3MBTL1ALDH1A1DDB1CRBN | |
| SCHEMBL7015222 | 0.74 | AHR (0.54) | AHRHPGDMAPTPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |