Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654484 | 0.83 | LMNA (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10653805 | 0.74 | PABPC1 (0.43) | PABPC1EGFRKDM4EKMT2AALDH1A1 | |
| SCHEMBL10654409 | 0.73 | PABPC1 (0.42) | PABPC1EGFRSRCKDM4EMAPT | |
| SCHEMBL10916358 | 0.72 | PABPC1 (0.37) | PABPC1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10655784 | 0.71 | PABPC1 (0.38) | PABPC1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10655975 | 0.70 | KDM4E (0.45) | PABPC1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL11269382 | 0.69 | HPGD (0.39) | EGFRSRCKDM4EMAPTMEN1 | |
| SCHEMBL10654396 | 0.69 | ALDH1A1 (0.38) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10654954 | 0.69 | KDM4E (0.47) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9754555 | 0.67 | GPR3 (0.48) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596814-A | Antiallergens | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| US-4503236-A | Antiallergic 4Hfuro[3,2-b]indoles | WARNER-LAMBERT COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |