Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653805 | 0.88 | PABPC1 (0.43) | PABPC1EGFRALDH1A1KDM4EHPGD | |
| SCHEMBL10654374 | 0.84 | LMNA (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10654954 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL10654943 | 0.75 | KDM4E (0.36) | PABPC1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10653052 | 0.74 | ALDH1A1 (0.36) | PABPC1EGFRSRCALDH1A1KDM4E | |
| SCHEMBL10918652 | 0.73 | PABPC1 (0.41) | PABPC1EGFRSRCALDH1A1KDM4E | |
| SCHEMBL14236771 | 0.73 | ALDH1A1 (0.50) | PABPC1EGFRSRCALDH1A1KDM4E | |
| SCHEMBL10653794 | 0.73 | LMNA (0.43) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL11269004 | 0.72 | EGFR (0.43) | EGFRSRCALDH1A1KDM4EHPGD | |
| SCHEMBL10654033 | 0.72 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4596814-A | Antiallergens | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| US-4503236-A | Antiallergic 4Hfuro[3,2-b]indoles | WARNER-LAMBERT COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |