Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RASGRP3 | Q8IV61 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923317 | 0.88 | ALDH1A1 (0.36) | MAPTKMT2ATP53ALDH1A1TDP1 | |
| SCHEMBL10748490 | 0.85 | TDP2 (0.38) | HRH2HRH1MAPTKMT2AGAA | |
| SCHEMBL10913839 | 0.83 | HRH2 (0.40) | HRH2HRH1MAPTKMT2AGAA | |
| SCHEMBL10914189 | 0.82 | ACHE (0.39) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL10911579 | 0.82 | ALDH1A1 (0.39) | HRH2HRH1MAPTKMT2AGAA | |
| SCHEMBL10913633 | 0.79 | LMNA (0.40) | HRH2HRH1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10911009 | 0.79 | TDP1 (0.39) | HRH2HRH1MAPTGAAL3MBTL1 | |
| SCHEMBL10913623 | 0.78 | KMT2A (0.35) | HRH2HRH1MAPTKMT2AGAA | |
| SCHEMBL11006059 | 0.76 | SMN1; SMN2 (0.39) | MAPTKMT2AGAATP53L3MBTL1 | |
| SCHEMBL10913091 | 0.76 | MAPT (0.43) | HRH2HRH1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088940-B1 | PYRIDINE-CARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BAYER AG (DE) | 1986-05-21 | — | — | EP | disclosed |