Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923869 | 0.99 | OPRM1 (0.52) | OPRM1OPRD1DRD2DRD3DRD4 | |
| Norpipanone SCHEMBL25085 | 0.80 | OPRM1 (0.75) | OPRM1OPRD1DRD2DRD3CYP2D6 | |
| Norpipanone SCHEMBL316886 | 0.79 | OPRM1 (0.73) | OPRM1OPRD1DRD2DRD3CYP2D6 | |
| SCHEMBL10926585 | 0.76 | OPRM1 (0.64) | OPRM1OPRD1DRD2DRD3DRD4 | |
| SCHEMBL10925815 | 0.76 | CYP3A4 (0.51) | OPRM1DRD2DRD3DRD4CYP2D6 | |
| SCHEMBL219257 | 0.75 | CHRM2 (0.60) | OPRM1OPRD1DRD2DRD3CYP2D6 | |
| Fenpipramide SCHEMBL149504 | 0.75 | CHRM2 (0.60) | OPRM1OPRD1DRD2DRD3CYP2D6 | |
| Hydrochloric Acid SCHEMBL10925999 | 0.75 | KCNA3 (0.67) | OPRM1DRD2DRD3DRD4CYP2D6 | |
| Fenpipramide SCHEMBL11716116 | 0.75 | OPRM1 (0.56) | OPRM1OPRD1DRD2DRD3CYP2D6 | |
| SCHEMBL10768406 | 0.75 | OPRM1 (0.63) | OPRM1OPRD1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4564641-A | ANTIDEPRESSANTS | BASF AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |