Norpipanone

Norpipanone

SCHEMBL25085

CCC(=O)C(CCN1CCCCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 6/20 0.75
OPRD1 P41143 1/20 0.75
CYP2D6 P10635 6/20 0.59
CHRM2 P08172 6/20 0.59
CHRM1 P11229 6/20 0.59
KCNH2 Q12809 4/20 0.59
HTR1A P08908 3/20 0.59
LMNA P02545 2/20 0.59
MAPK1 P28482 2/20 0.57
DRD2 P14416 2/20 0.54
DRD3 P35462 2/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CHRM3 P20309 5/20 0.52
CHRM4 P08173 4/20 0.52
CHRM5 P08912 4/20 0.52
SIGMAR1 Q99720 2/20 0.52
KDM4E B2RXH2 1/20 0.52
DRD1 P21728 1/20 0.52
HTR2A P28223 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Norpipanone SCHEMBL316886 0.99 OPRM1 (0.73) OPRM1OPRD1CYP2D6CHRM2CHRM1
Fenpipramide SCHEMBL149504 0.87 CHRM2 (0.60) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL219257 0.87 CHRM2 (0.60) OPRM1OPRD1CYP2D6CHRM2CHRM1
Fenpipramide SCHEMBL11716116 0.86 OPRM1 (0.56) OPRM1OPRD1CYP2D6CHRM2CHRM1
Fenpipramide SCHEMBL7558279 0.85 CHRM2 (0.59) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL10768406 0.83 OPRM1 (0.63) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL1492481 0.83 OPRM1 (0.63) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL10923869 0.81 OPRM1 (0.52) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL11722508 0.81 CYP2D6 (0.57) OPRM1OPRD1CYP2D6CHRM2CHRM1
SCHEMBL10924613 0.80 OPRM1 (0.53) OPRM1OPRD1CYP2D6CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6035 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed