Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenpipramide SCHEMBL149504 | 0.96 | CHRM2 (0.60) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL219257 | 0.96 | CHRM2 (0.60) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| Fenpipramide SCHEMBL7558279 | 0.94 | CHRM2 (0.59) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| Norpipanone SCHEMBL25085 | 0.86 | OPRM1 (0.75) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| Norpipanone SCHEMBL316886 | 0.84 | OPRM1 (0.73) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL8880422 | 0.84 | CHRM2 (0.47) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL9248078 | 0.81 | KMT2A (0.57) | OPRM1OPRD1LMNAHTR1AKMT2A | |
| SCHEMBL10768406 | 0.81 | OPRM1 (0.63) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL1492481 | 0.81 | OPRM1 (0.63) | OPRM1OPRD1CYP2D6CHRM2CHRM1 | |
| SCHEMBL11722508 | 0.79 | CYP2D6 (0.57) | OPRM1OPRD1CYP2D6CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017630-A | Certain diphenylalkanoamides used as bird and murine repellents | THE UPJOHN COMPANY (US) | 1977-04-12 | — | — | US | disclosed |