Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398120 | 0.79 | BCHE (0.58) | MGLLMEN1KMT2ADRD2DRD3 | |
| SCHEMBL6398124 | 0.79 | BCHE (0.58) | MGLLMEN1KMT2ADRD2DRD3 | |
| SCHEMBL11747892 | 0.79 | KCNH2 (0.64) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8155672 | 0.79 | KDM2B (0.71) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL9380802 | 0.79 | KCNH2 (0.64) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8105866 | 0.78 | MGLL (0.56) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL6397433 | 0.77 | ALDH1A1 (0.63) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL11519875 | 0.77 | KCNH2 (0.62) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8149814 | 0.76 | HTR2A (0.58) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8154756 | 0.76 | MGLL (0.54) | MGLLMEN1KMT2AKCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197488-A2 | 1,4-Dihydropyiridine derivative, a process for preparing the same, a pharmaceutical composition as well as the use thereof | Eisai Co., Ltd. (JP) | 1986-10-15 | — | — | EP | disclosed |