Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105866 | 0.83 | MGLL (0.56) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL9380802 | 0.77 | KCNH2 (0.64) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL11747892 | 0.77 | KCNH2 (0.64) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL8155672 | 0.77 | KDM2B (0.71) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL10926545 | 0.76 | MGLL (0.60) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL6397433 | 0.75 | ALDH1A1 (0.63) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL11519875 | 0.75 | KCNH2 (0.62) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL6009245 | 0.74 | MGLL (0.54) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL8154756 | 0.74 | MGLL (0.54) | HTR2AKCNH2MGLLMEN1KMT2A | |
| SCHEMBL14638479 | 0.74 | MGLL (0.61) | KCNH2MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |