Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155672 | 0.80 | KDM2B (0.71) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8096313 | 0.77 | LMNA (0.60) | MGLLMEN1KMT2AKCNH2LMNA | |
| SCHEMBL11747892 | 0.77 | KCNH2 (0.64) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL9380802 | 0.77 | KCNH2 (0.64) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL5758023 | 0.77 | HTR2A (0.61) | KCNH2HTR2AKDM4E | |
| SCHEMBL10926545 | 0.76 | MGLL (0.60) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL8105866 | 0.76 | MGLL (0.56) | MGLLMEN1KMT2AKCNH2HTR2A | |
| SCHEMBL4042398 | 0.76 | HTR2A (0.62) | KCNH2HTR2ALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6008822 | 0.76 | HTR2A (0.60) | KCNH2HTR2AKDM4E | |
| SCHEMBL24135454 | 0.76 | KCNH2 (0.79) | MEN1KMT2AKCNH2HTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |