Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GSDMD | P57764 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937374 | 0.79 | ABCB11 (0.38) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL20326250 | 0.77 | CHRM1 (0.35) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL10939017 | 0.76 | CHRM1 (0.43) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL1057983 | 0.75 | — | — | |
| SCHEMBL10935851 | 0.73 | TP53 (0.33) | RNPEPTP53 | |
| SCHEMBL17011121 | 0.73 | ABCB11 (0.44) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL6137839 | 0.72 | HDAC1 (0.37) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL2417198 | 0.71 | ALDH1A1 (0.35) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL17666043 | 0.71 | PGR (0.31) | HTR2AHRH1PGRADRA2AADRA2B | |
| SCHEMBL20165513 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554108-A | Alkali carboxyalkyl dithiocarbamates and use as ore flotation reagents | PHILLIPS PETROLEUM COMPANY (US) | 1985-11-19 | — | — | US | claimed |
| CN-110035829-B | Depressant composition and method for depressing gangue sulfide minerals during flotation of sulfide ores | 塞特工业公司 | 2021-12-24 | — | — | CN | disclosed |
| US-10710099-B2 | Compositions and methods for selective separation of minerals from sulfide ores | CYTEC INDUSTRIES INC. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190336984-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES | CYTEC INDUSTRIES INC. (US) | 2019-11-07 | — | — | US | disclosed |
| US-10369577-B2 | Compositions and methods for selective separation of minerals from sulfide ores | CYTEC INDUSTRIES INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180099293-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES | CYTEC INDUSTRIES INC. | 2018-04-12 | — | — | US | disclosed |
| US-4554068-A | DITHIOCARBAMATES AS SUPPRESSANTS | PHILLIPS PETROLEUM COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4554108-A | Alkali carboxyalkyl dithiocarbamates and use as ore flotation reagents | PHILLIPS PETROLEUM COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10369577-B2 | Compositions and methods for selective separation of minerals from sulfide ores | TST, CTH, PFAS | ABCB11 3796/4885CYP2E1 3075/4885PTGS1 2742/4885 |
| US-20190336984-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES | TST, CTH, PFAS | ABCB11 3796/4885CYP2E1 3075/4885PTGS1 2742/4885 |
| US-10710099-B2 | Compositions and methods for selective separation of minerals from sulfide ores | TST, CTH, PFAS | ABCB11 3796/4885CYP2E1 3075/4885PTGS1 2742/4885 |
| US-20180099293-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE SEPARATION OF MINERALS FROM SULFIDE ORES | TST, CTH, PFAS | ABCB11 3796/4885CYP2E1 3075/4885PTGS1 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.