Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176919 | 0.85 | AKR1C3 (0.44) | HSP90AA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10939109 | 0.84 | HSP90AA1 (0.45) | HSP90AA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11072131 | 0.82 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11070853 | 0.82 | ALDH1A1 (0.39) | MAPTMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL11164835 | 0.81 | HSP90AA1 (0.39) | HSP90AA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11169944 | 0.78 | KMT2A (0.38) | HSP90AA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11160025 | 0.77 | ACHE (0.46) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL10800979 | 0.76 | ACHE (0.42) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11165237 | 0.74 | LMNA (0.40) | HSP90AA1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10831575 | 0.73 | SMN1; SMN2 (0.42) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |