Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391211 | 0.87 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL5603448 | 0.87 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL650610 | 0.87 | ACE (0.59) | ACEMMEMMEL1 | |
| SCHEMBL7380315 | 0.83 | MMEL1 (0.64) | ACEMMEMMEL1 | |
| SCHEMBL7385743 | 0.83 | MMEL1 (0.64) | ACEMMEMMEL1 | |
| SCHEMBL7385019 | 0.81 | MME (0.64) | ACEMMEMMEL1 | |
| Water SCHEMBL10949495 | 0.81 | MME (0.62) | ACEMMEMMEL1 | |
| SCHEMBL11296564 | 0.80 | ATM (0.52) | ACEMME | |
| SCHEMBL9068701 | 0.78 | FOLH1 (0.52) | — | |
| SCHEMBL7375696 | 0.77 | ACE (0.53) | ACEMMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054862-B1 | SUBSTITUTED DIPEPTIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE INHIBITION OF ENKEPHALINASE | SCHERING CORPORATION (US) | 1985-11-27 | — | — | EP | claimed |
| EP-0054862-A1 | Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase | SCHERING CORPORATION (US) | 1982-06-30 | — | — | EP | claimed |
| EP-0054862-A1 | Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase | SCHERING CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |