SCHEMBL10944872

SCHEMBL10944872

O=S(=O)(O)c1ccc2nc(Cl)sc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.49
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 3/20 0.49
PKM P14618 2/20 0.49
LMNA P02545 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 1/20 0.49
MEN1 O00255 4/20 0.46
RECQL P46063 1/20 0.45
ACP1 P24666 1/20 0.43
POLB P06746 3/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 1/20 0.43
ATM Q13315 1/20 0.43
VDR P11473 1/20 0.43
GFER P55789 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
CYP3A4 P08684 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7753231 0.98 KMT2A (0.47) KMT2AALDH1A1KDM4EPKMLMNA
Hydrochloric Acid SCHEMBL11473358 0.85 ALDH1A1 (0.43) ALDH1A1KDM4EPKMPOLBCYP3A4
SCHEMBL1094028 0.85 KMT2A (0.50) KMT2AALDH1A1KDM4EPKMLMNA
SCHEMBL1747940 0.83 MEN1 (0.59) KMT2AALDH1A1KDM4ELMNAHPGD
SCHEMBL22654667 0.83 PKM (0.61) KMT2AALDH1A1KDM4EPKMLMNA
SCHEMBL14020160 0.80 HSD17B1 (0.50) KMT2AALDH1A1KDM4EPKMLMNA
SCHEMBL83871 0.80 LMNA (0.57) KMT2AALDH1A1PKMLMNAMEN1
SCHEMBL1498187 0.80 ALDH1A1 (0.76) KMT2AALDH1A1KDM4EPKMLMNA
SCHEMBL22230068 0.80 KMT2A (0.51) KMT2AALDH1A1KDM4EPKMLMNA
SCHEMBL22230114 0.80 ILK (0.54) KMT2AALDH1A1KDM4EPKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4534908-A Water-soluble disazo compounds and new bis-(aminophenoxy)-ethane compounds having fiber-reactive groups as the tetrazo components, and use of the disazo compounds as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-13 US disclosed
US-4501763-A REPARING ISOTONIZED MIXTURE MORINAGA MILK INDUSTRY CO., LTD. (JP) 1985-02-26 US disclosed
EP-0071168-B1 WATER-SOLUBLE DISAZO COMPOUNDS AND BIS-(AMINO-PHENOXY)-ETHANE COMPOUNDS WITH FIBRE REACTIVE GROUPS AS TETRAZO COMPOUNDS, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AND THE USE OF THE DISAZO COMPOUNDS AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-30 EP disclosed
US-4394310-A DIAZOTIZATION, CYCLIZATION HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-19 US disclosed
EP-0071168-A2 Water-soluble disazo compounds and bis-(amino-phenoxy)-ethane compounds with fibre reactive groups as tetrazo compounds, process for the preparation of these compounds and the use of the disazo compounds as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-09 EP disclosed