SCHEMBL10946372

SCHEMBL10946372

NP(O)Oc1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 1/20 0.48
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
GAA P10253 1/20 0.44
RCE1 Q9Y256 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
PTPN7 P35236 1/20 0.43
MEN1 O00255 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP3A4 P08684 1/20 0.41
CA7 P43166 1/20 0.41
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946368 0.83 CYP2A6 (0.52) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL4238279 0.83 CYP1A2 (0.52) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL11587475 0.83 CYP1A2 (0.52) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL3960261 0.78 CYP2A6 (0.56) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL3862133 0.77 ALDH1A1 (0.31) TDP1KMT2AMEN1ALDH1A1CYP3A4
Catechol SCHEMBL10934697 0.76 ALOX5 (0.50) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL28167104 0.76 CYP1A2 (0.45) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL21548080 0.75 LTA4H (0.41) CA1CA2CA9ALDH1A1
SCHEMBL8397144 0.74 CYP2A6 (0.52) AGXTCYP1A2CYP2A6CA1CA2
SCHEMBL27619363 0.74 CYP2A6 (0.52) AGXTCYP1A2CYP2A6CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4501684-A STABILIZERS FOR POLYMERS THE B. F. GOODRICH COMPANY (US) 1985-02-26 US claimed
US-4501684-A STABILIZERS FOR POLYMERS THE B. F. GOODRICH COMPANY (US) 1985-02-26 US disclosed