Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750340 | 0.86 | PDE3B (0.39) | ARKDM4EPDE3BPDE3AMAPT | |
| SCHEMBL10957578 | 0.74 | ADORA3 (0.42) | KDM4EPDE3BPDE3AALDH1A1HSD17B10 | |
| SCHEMBL10957936 | 0.70 | CYP1A2 (0.47) | ARKDM4EPDE3BPDE3AMAPT | |
| SCHEMBL10750346 | 0.70 | ADRA2A (0.42) | KDM4EPDE3BPDE3AMAPTALDH1A1 | |
| SCHEMBL10767817 | 0.68 | ALDH1A1 (0.43) | KDM4EPDE3BPDE3AMAPTALDH1A1 | |
| SCHEMBL10958062 | 0.68 | KDM4E (0.40) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL10956542 | 0.67 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL10778414 | 0.66 | PDE3B (0.40) | KDM4EPDE3BPDE3AALDH1A1HSD17B10 | |
| SCHEMBL10958050 | 0.65 | ADRA2A (0.39) | KDM4EPDE3BPDE3AMAPTALDH1A1 | |
| SCHEMBL10957654 | 0.65 | KDM4E (0.51) | KDM4EMAPTALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176333-A2 | Substituted quinazolinediones | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-04-02 | — | — | EP | disclosed |