Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10965609 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2ADRD2HTR1AHTR7 | |
| SCHEMBL10915707 | 0.84 | MEN1 (0.51) | MEN1KMT2AHTR1AHTR2AHTR7 | |
| SCHEMBL10967335 | 0.78 | KDM4E (0.48) | MEN1KMT2ADRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10914569 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2ADRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10971146 | 0.75 | CCR5 (0.46) | MEN1KMT2ADRD2CHRM4DRD4 | |
| Hydrochloric Acid SCHEMBL10915699 | 0.74 | SIGMAR1 (0.49) | MEN1KMT2ADRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10972048 | 0.74 | KDM4E (0.47) | MEN1KMT2ADRD2CHRM4NR3C1 | |
| Hydrochloric Acid SCHEMBL10970085 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2ADRD2HTR7GAA | |
| SCHEMBL10967209 | 0.73 | POLB (0.50) | MEN1KMT2ADRD2HTR2ADRD4 | |
| SCHEMBL10970591 | 0.72 | ALDH1A1 (0.47) | DRD2CHRM4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064706-B1 | 5-(4-PHENYL-1-PIPERIDINYL)METHYL-2,3-DIHYDRO-2-OXO-1H-IMIDAZOLE-4-CARBOXYLIC ACID DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-03 | — | — | EP | disclosed |
| EP-0064706-A1 | 5-(4-Phenyl-1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4329470-A | CORDIOTONIC, HYPOTENSIVE, ANTITHROMBOSIS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |