Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | CCR1 | P32246 | 7/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10915699 | 0.91 | SIGMAR1 (0.49) | MEN1KMT2ACCR5SIGMAR1HTR1A | |
| SCHEMBL10968588 | 0.84 | MEN1 (0.46) | MEN1KMT2ACHRM4NR3C1PARP1 | |
| Hydrochloric Acid SCHEMBL10917762 | 0.84 | PDE3B (0.51) | MEN1KMT2APARP1CCR5SIGMAR1 | |
| SCHEMBL10918581 | 0.83 | HTR1A (0.53) | KMT2AHTR1AHTR2AHTR7 | |
| SCHEMBL10914047 | 0.82 | HSD11B1 (0.50) | CHRM4NR3C1SIGMAR1 | |
| SCHEMBL10967335 | 0.82 | KDM4E (0.48) | MEN1KMT2ANR3C1PARP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10916739 | 0.82 | HSD11B1 (0.49) | CHRM4NR3C1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10916193 | 0.81 | DRD2 (0.47) | KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL10914569 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2ASIGMAR1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10965609 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2ACHRM4NR3C1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064707-B1 | 4-(4-PHENYL-1-PIPERIDINYL)METHYL-5-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| US-4329471-A | CARDIOTONICS, HYPOTENSIVE AGENTS, AND ANTITHROMBOTIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |