Sugi Predict

Sugi Predict / Compounds / SCHEMBL1096908

SCHEMBL1096908

SCHEMBL1096908

CCCC[C@@](N)(C(=O)O)[C@@H](C)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ARG1 P05089 3/20 0.46
▸ ARG2 P78540 2/20 0.46
▸ ODC1 P11926 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ PMP22 Q01453 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ FDPS P14324 3/20 0.38
▸ CA2 P00918 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ CA1 P00915 1/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ SPTLC1 O15269 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14689712 0.84 ARG1 (0.62) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL14764493 0.78 ODC1 (0.49) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL3110575 0.78 ARG1 (0.38) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL3110569 0.78 ARG1 (0.38) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL28009580 0.77 ARG1 (0.64) ARG1ARG2ODC1KDM4ELMNA
Water SCHEMBL27925668 0.77 ARG1 (0.64) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL16222764 0.76 ARG1 (0.37) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL16222670 0.76 ARG1 (0.37) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL8981541 0.76 GRM2 (0.40) ARG1ARG2ODC1KDM4ELMNA
SCHEMBL6757381 0.76 ARG1 (0.49) ARG1ARG2ODC1KDM4EFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100029646-A1 PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS TOPO TARGET A/S (DK) 2010-02-04 — — US claimed
CN-115916343-B New use of halogenated xanthenes in oncology and virology 普罗维克图斯药品技术公司 2024-07-02 — — CN disclosed
US-11975106-B2 Uses of halogenated xanthenes in oncology and virology PROVECTUS PHARMATECH, INC. (US) 2024-05-07 — — US disclosed
CN-115916343-A New use of halogenated xanthenes in oncology and virology 普罗维克图斯药品技术公司 2023-04-04 — — CN disclosed
EP-4103283-A1 NOVEL USES OF HALOGENATED XANTHENES IN ONCOLOGY AND VIROLOGY Provectus Pharmatech, Inc. (US) 2022-12-21 — — EP disclosed
WO-2021195400-A1 NOVEL USES OF HALOGENATED XANTHENES IN ONCOLOGY AND VIROLOGY PROVECTUS PHARMATECH, INC. (US) 2021-09-30 — — WO disclosed
US-20210299083-A1 Novel Uses of Halogenated Xanthenes in Oncology and Virology PROVECTUS PHARMATECH, INC. (US) 2021-09-30 — — US disclosed
US-8153365-B2 Oligonucleotide analogues EXIQON A/S (DK) 2012-04-10 — — US disclosed
US-8034909-B2 Oligonucleotide analogues EXIQON A/S (DK) 2011-10-11 — — US disclosed
US-20110245327-A1 Oligonucleotide Analogues EXIQON A/S (DK) 2011-10-06 — — US disclosed
EP-2341058-A2 Oligonucleotide Analogues Exiqon A/S (DK) 2011-07-06 — — EP disclosed
US-20100029646-A1 PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS TOPO TARGET A/S (DK) 2010-02-04 — — US disclosed
US-20080227847-A1 Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use ADITECH PHARMA AB (SE) 2008-09-18 — — US disclosed
US-6136580-A POLYPEPTIDE WITH ENZYMATIC ACTIVITY; FOR DIAGNOSIS, PREVENTION AND TREATMENT OF INFLAMMATION, TUMOR METASTASIS AND TISSUE REJECTION; ANTITUMOR AGENTS THE BURNHAM INSTITUTE (US) 2000-10-24 — — US disclosed
EP-0722321-A4 SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS UNIV FLORIDA STATE (US) 1998-04-15 — — EP disclosed
EP-0722436-A4 MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS UNIV FLORIDA STATE (US) 1996-11-20 — — EP disclosed
EP-0722321-A1 SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS FLORIDA STATE UNIVERSITY (US) 1996-07-24 — — EP disclosed
EP-0722436-A1 MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS FLORIDA STATE UNIVERSITY (US) 1996-07-24 — — EP disclosed
WO-1995009833-A1 MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS FLORIDA STATE UNIVERSITY (US) 1995-04-13 — — WO disclosed
WO-1995009620-A1 SULFOXIMINE AND SULFODIIMINE MATRIX METALLOPROTEINASE INHIBITORS FLORIDA STATE UNIVERSITY (US) 1995-04-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299083-A1 Novel Uses of Halogenated Xanthenes in Oncology and Virology IRF3, IFNAR1, IFNG ARG1 903/4885ARG2 2681/4885ODC1 3082/4885
US-20110245327-A1 Oligonucleotide Analogues POLRMT, POLM, POLN ARG1 4884/4885ARG2 4802/4885ODC1 594/4885
US-11975106-B2 Uses of halogenated xanthenes in oncology and virology IFNG, IRF3, IFNAR1 ARG1 601/4885ARG2 2484/4885ODC1 3305/4885
US-20080227847-A1 Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use FAH, SLC16A1, FH ARG1 1321/4885ARG2 616/4885ODC1 700/4885
US-20100029646-A1 PRODRUGS OF DIPHENYL OX-INDOL-2-ONE COMPOUNDS IDO1, IDO2, TDO2 ARG1 865/4885ARG2 269/4885ODC1 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.