Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752287 | 0.85 | MEN1 (0.44) | POLBTP53MAPTPTGDR2KDM1A | |
| SCHEMBL10973111 | 0.79 | HDAC6 (0.39) | ALDH1A1 | |
| SCHEMBL10972161 | 0.78 | USP2 (0.40) | MAPTALDH1A1TSHR | |
| SCHEMBL14861373 | 0.77 | TDP1 (0.48) | NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL9315961 | 0.77 | POLB (0.61) | POLBTP53MAPTPTGDR2KDM1A | |
| SCHEMBL10973105 | 0.77 | POLB (0.49) | POLBTP53MAPTPTGDR2KDM1A | |
| SCHEMBL2226376 | 0.75 | SMN1; SMN2 (0.51) | POLBNPC1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3968828 | 0.75 | CCR6 (0.54) | KAT2BALDH1A1 | |
| SCHEMBL8579394 | 0.74 | SMN1; SMN2 (0.61) | POLBTP53MAPTPTGDR2KDM1A | |
| SCHEMBL10977964 | 0.74 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |