Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752292 | 0.85 | HDAC6 (0.37) | HDAC6RENTDP1OPRM1OPRD1 | |
| SCHEMBL10973108 | 0.79 | POLB (0.48) | ALDH1A1 | |
| SCHEMBL10972161 | 0.76 | USP2 (0.40) | HDAC6RENTDP1OPRM1OPRD1 | |
| SCHEMBL14861373 | 0.76 | TDP1 (0.48) | HDAC6RENTDP1OPRM1OPRD1 | |
| SCHEMBL10752184 | 0.72 | PKM (0.52) | ALDH1A1KMT2ALTA4H | |
| SCHEMBL10977964 | 0.72 | ALDH1A1 (0.47) | TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL2226376 | 0.71 | SMN1; SMN2 (0.51) | RENTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL7304372 | 0.71 | CYP1A2 (0.44) | HDAC6ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6936315 | 0.71 | TSHR (0.41) | TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3968828 | 0.71 | CCR6 (0.54) | TDP1ALDH1A1KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |