Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972161 | 0.82 | USP2 (0.40) | ALDH1A1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL10749977 | 0.81 | MC4R (0.44) | ALDH1A1LMNASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL21461681 | 0.76 | KCNH2 (0.53) | ALDH1A1MAPTKCNH2 | |
| SCHEMBL1350599 | 0.74 | MAPT (0.55) | ALDH1A1MAPTKMT2ATDP1KCNH2 | |
| SCHEMBL10533251 | 0.74 | NR1D1 (0.57) | ALDH1A1CRHBPCRHR2MAPTKCNH2 | |
| SCHEMBL1350027 | 0.74 | MAPT (0.57) | ALDH1A1MAPTMAPK1KMT2AL3MBTL1 | |
| SCHEMBL2104567 | 0.74 | CRHBP (0.54) | ALDH1A1LMNASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL14861373 | 0.74 | TDP1 (0.48) | ALDH1A1LMNAMAPK1KMT2ATDP1 | |
| SCHEMBL2876660 | 0.74 | TSHR (0.50) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL10973108 | 0.74 | POLB (0.48) | ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149534-A2 | Novel thioketene derivatives and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-24 | — | — | EP | disclosed |