Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894966 | 0.89 | SIGMAR1 (0.35) | ALDH1A1MAPTTSHRHTTDRD2 | |
| SCHEMBL8903406 | 0.75 | ACHE (0.32) | — | |
| SCHEMBL250168 | 0.66 | HSD17B10 (0.42) | HSD17B10ALDH1A1HPGDMAPTTSHR | |
| SCHEMBL27672561 | 0.65 | HPGD (0.35) | ALDH1A1HPGDMAPTTSHRMAPK1 | |
| SCHEMBL27603207 | 0.58 | TMEM97 (0.51) | HSD17B10ALDH1A1HPGDMAPTTSHR | |
| Tiaramide SCHEMBL29376518 | 0.57 | NPY5R (0.58) | TSHRTMEM97 | |
| SCHEMBL5249019 | 0.55 | KMT2A (0.66) | ALDH1A1MAPTMAPK1HTTMEN1 | |
| SCHEMBL2087116 | 0.55 | ALDH1A1 (0.46) | HSD17B10ALDH1A1HPGDMAPTTSHR | |
| SCHEMBL235856 | 0.53 | — | — | |
| SCHEMBL3971866 | 0.53 | ALDH1A1 (0.65) | HSD17B10ALDH1A1HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58052281-A | — | — | None | — | — | JP | disclosed |
| JP-57118576-A | — | — | None | — | — | JP | disclosed |
| JP-57165381-A | — | — | None | — | — | JP | disclosed |
| JP-60228468-A | — | — | None | — | — | JP | disclosed |
| JP-56020582-A | — | — | None | — | — | JP | disclosed |
| JP-55100373-A | — | — | None | — | — | JP | disclosed |
| JP-55000345-A | — | — | None | — | — | JP | disclosed |
| JP-S60228468-A | 1,2-BIS(2-OXO-3-BENZOTHIAZOLINYL)ETHANONE AND PREPARATION THEREOF | ARAKAWA CHIYOUTAROU KK | 1985-11-13 | — | — | JP | disclosed |
| JP-S5852281-A | BENZOTHIAZOLINONE DERIVATIVE AND ITS PREPARATION | SHIONO KORYO KK | 1983-03-28 | — | — | JP | disclosed |
| JP-S57165381-A | NOVEL PIPERAZING DERIVATIVE AND ITS PREPARATION | KANO SHINZO | 1982-10-12 | — | — | JP | disclosed |
| JP-S57118576-A | PREPARATION OF 5-CHLORO-3-(4-(2-HYDROXYETHYL)-1- PIPERAZINYL)-CARBONYLMETHYL-2-BENZOTHIAZOLINONE OR SALT THEREOF | HAMARI YAKUHIN KOGYO KK | 1982-07-23 | — | — | JP | disclosed |
| JP-S5620582-A | NOVEL 2-BENZOTHIAZOLINONE DERIVATIVE AND ITS PREPARATION | HAMARI YAKUHIN KOGYO KK | 1981-02-26 | — | — | JP | disclosed |
| JP-S55100373-A | PREPARATION OF ACID AMIDE | SHIONO KORYO KK | 1980-07-31 | — | — | JP | disclosed |
| JP-S55345-A | 2-IMINOBENZTHIAZOLINE DERIVATIVE | IWAKI SEIYAKU KK | 1980-01-05 | — | — | JP | disclosed |