Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ADA | P00813 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077123 | 0.76 | NNMT (0.45) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22458325 | 0.75 | FGFR1 (0.45) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL9663409 | 0.73 | MARS1 (0.58) | ALDH1A1ADORA2A | |
| SCHEMBL1577868 | 0.71 | ADORA2A (0.46) | CYP3A4ALDH1A1ADORA2A | |
| SCHEMBL2365052 | 0.71 | ASAH1 (0.44) | FGFR1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6897158 | 0.70 | ALDH1A1 (0.34) | ALDH1A1ADORA2A | |
| SCHEMBL8849512 | 0.69 | FGFR1 (0.41) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL30254206 | 0.68 | P2RX7 (0.53) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL7271295 | 0.68 | FDPS (0.49) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL29782820 | 0.68 | ADA (0.43) | FDPSFGFR1FGFR4ADAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |