SCHEMBL1097615

SCHEMBL1097615

C[Si](C)(C)Sc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MGLL Q99685 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ALDH1A1 P00352 5/20 0.39
MAPK1 P28482 1/20 0.39
MAOA P21397 2/20 0.34
MAOB P27338 2/20 0.34
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
FFAR1 O14842 1/20 0.32
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTT P42858 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10406863 0.90 ALDH1A1 (0.47) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL9135801 0.84 KDM4E (0.30) HSD17B10KDM4E
SCHEMBL10410663 0.80 MAPT (0.30) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL10409167 0.77 NR1H2 (0.41) HPGDALDH1A1MAPK1MAOAMAOB
SCHEMBL10409186 0.77 SLC2A1 (0.30)
SCHEMBL16378132 0.76 MAPT (0.39) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL31623407 0.75 HPGD (0.50) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL10913570 0.74 ACHE (0.44) MAPTSMN1; SMN2ALDH1A1LMNAACHE
SCHEMBL10977568 0.74 MAPT (0.38) HPGDMAPTSMN1; SMN2MGLLHSD17B10
SCHEMBL10583453 0.73 KDM4E (0.33) HPGDMAPTSMN1; SMN2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735661-A1 INHERENT AREA SELECTIVE DEPOSITION OF SILICON-CONTAINING DIELECTRIC ON METAL SUBSTRATE GELEST, INC. (US) 2026-05-06 EP claimed
US-20250364558-A1 CONCENTRATION GRADIENT-TYPE NEGATIVE ELECTRODE ACTIVE MATERIAL FOR SECONDARY BATTERY AND METHOD FOR MANUFACTURING SAME SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION (KR) 2025-11-27 US claimed
US-20250311261-A1 METHOD FOR SEMICONDUCTOR PROCESSING TOKYO ELECTRON LIMITED (JP) 2025-10-02 US claimed
US-12381076-B2 Inherent area selective deposition of silicon-containing dielectric on metal substrate GELEST, INC. (US) 2025-08-05 US claimed
WO-2025061195-A1 POLYPEPTOID AND PREPARATION METHOD THEREFOR 北京聚肽生物科技有限公司 2025-03-27 WO claimed
CN-119684594-A Cluster peptide and preparation method thereof 北京聚肽生物科技有限公司 2025-03-25 CN claimed
US-20250095982-A1 INHERENT AREA SELECTIVE DEPOSITION OF SILICON-CONTAINING DIELECTRIC ON METAL SUBSTRATE GELEST, INC. 2025-03-20 US claimed
WO-2025053926-A1 INHERENT AREA SELECTIVE DEPOSITION OF SILICON-CONTAINING DIELECTRIC ON METAL SUBSTRATE GELEST, INC. (US) 2025-03-13 WO claimed
CN-119390627-A Synthesis method of photocatalytic asymmetric thioether compound 中国人民解放军军事科学院防化研究院 2025-02-07 CN claimed
CN-117054662-A KIM-1 chemiluminescence kit 宁波海尔施智造有限公司 2023-11-14 CN claimed
JP-3553086-B2 2004-08-11 JP claimed
US-20030086984-A1 Pharmaceutical compositions having appetite suppressant activity CSIR 2003-05-08 US claimed
US-20020168427-A1 Pharmaceutical compositions having appetite suppressant activity CSIR 2002-11-14 US claimed
EP-1222927-A2 Pharmaceutical compositions having appetite suppressant activity CSIR (ZA) 2002-07-17 EP claimed
JP-2000510482-A 2000-08-15 JP claimed
EP-0973534-A1 PHARMACEUTICAL COMPOSITIONS HAVING APPETITE SUPPRESSANT ACTIVITY CSIR (ZA) 2000-01-26 EP claimed
WO-1998046243-A2 PHARMACEUTICAL COMPOSITIONS HAVING APPETITE SUPPRESSANT ACTIVITY CSIR (ZA) 1998-10-22 WO claimed
EP-0403600-A4 DEPROTECTION OF PROTECTED PEPTIDES 1991-03-13 EP claimed
EP-0403600-A1 DEPROTECTION OF PROTECTED PEPTIDES THE ROCKEFELLER UNIVERSITY (US) 1990-12-27 EP claimed
WO-1990002138-A1 DEPROTECTION OF PROTECTED PEPTIDES THE ROCKEFELLER UNIVERSITY (US) 1990-03-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020168427-A1 Pharmaceutical compositions having appetite suppressant activity GPR119, TPH1, TRHDE HPGD 1360/4885MAPT 3038/4885SMN1; SMN2 4080/4885
US-20030086984-A1 Pharmaceutical compositions having appetite suppressant activity TPH1, TRHDE, TRHR HPGD 1688/4885MAPT 3027/4885SMN1; SMN2 4315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.