Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757422 | 0.84 | ITGB3 (0.37) | MAPTALDH1A1LMNAKMT2ATDP1 | |
| SCHEMBL10977964 | 0.81 | ALDH1A1 (0.47) | CRHBPCRHR2MAPTALDH1A1LMNA | |
| SCHEMBL10749970 | 0.76 | — | — | |
| SCHEMBL10753221 | 0.76 | ALDH1A1 (0.48) | MAPTALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL10752287 | 0.75 | MEN1 (0.44) | MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL10752292 | 0.74 | HDAC6 (0.37) | ALDH1A1LMNATDP1 | |
| SCHEMBL21461681 | 0.72 | KCNH2 (0.53) | MAPTALDH1A1 | |
| SCHEMBL10533251 | 0.71 | NR1D1 (0.57) | CRHBPCRHR2MAPTALDH1A1 | |
| SCHEMBL1350599 | 0.71 | MAPT (0.55) | MAPTALDH1A1KMT2ATDP1 | |
| SCHEMBL1802673 | 0.71 | CRHBP (0.60) | CRHBPCRHR2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663319-A | LIVER DISORDERS | TANABE SEIYSKU CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |