Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95787 | 0.82 | TP53 (0.48) | NPC1RAB9AMEN1KMT2APYCR1 | |
| SCHEMBL4050941 | 0.74 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2APYCR1 | |
| SCHEMBL8186371 | 0.72 | NPSR1 (0.47) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL1909365 | 0.69 | PKM (0.61) | NPC1RAB9AKMT2APOLBSMN1; SMN2 | |
| SCHEMBL2702114 | 0.69 | ICMT (0.45) | NPC1RAB9AMEN1KMT2APSMB5 | |
| Adonitol SCHEMBL19182208 | 0.69 | ALDH1A1 (0.38) | NPC1RAB9AMEN1KMT2APYCR1 | |
| SCHEMBL14729157 | 0.69 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2APYCR1 | |
| SCHEMBL30919490 | 0.68 | PYCR1 (0.45) | NPC1RAB9AMEN1KMT2APYCR1 | |
| SCHEMBL16542323 | 0.68 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL12345571 | 0.68 | AMY1A (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60045583-A | — | — | None | — | — | JP | disclosed |
| JP-S6045583-A | SUGAR ALCOHOL KETAL COMPOUND OF TRIACETONAMINE | ADEKA ARGUS CHEM CO LTD | 1985-03-12 | — | — | JP | disclosed |