Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 4/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bifeprofen SCHEMBL2109705 | 0.84 | L3MBTL1 (0.44) | DPP4DPP7RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10980222 | 0.83 | ALDH1A1 (0.50) | MAPTRAB9ANPC1ALDH1A1HTT | |
| Bifeprofen SCHEMBL10989641 | 0.83 | NFE2L2 (0.45) | DPP4DPP7RAB9ASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL10990311 | 0.79 | MAPK1 (0.45) | DPP4DPP7PRCPSCD5ADAMTS5 | |
| SCHEMBL10401162 | 0.70 | ALDH1A1 (0.50) | KCNH2HRH3PRCPADAMTS5MAPT | |
| SCHEMBL10981141 | 0.70 | PTGS2 (0.66) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17787758 | 0.69 | ALDH1A1 (0.59) | KCNH2HRH3ADAMTS5MAPTRAB9A | |
| SCHEMBL4034093 | 0.68 | ALDH1A1 (0.57) | KCNH2HRH3ADAMTS5MAPTRAB9A | |
| SCHEMBL8903163 | 0.68 | YAP1 (0.58) | KCNH2HRH3ADAMTS5RAB9ASMN1; SMN2 | |
| SCHEMBL15840473 | 0.68 | ADAMTS5 (0.58) | KCNH2HRH3PRCPADAMTS5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510142-A | ANTIINFLAMMATORY OR ANALGESIC AGNET | PIERRE FABRE S.A. (FR) | 1985-04-09 | — | — | US | claimed |
| US-4510142-A | ANTIINFLAMMATORY OR ANALGESIC AGNET | PIERRE FABRE S.A. (FR) | 1985-04-09 | — | — | US | disclosed |