Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | RECQL | P46063 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 2/20 | 0.68 |
| ▸ | CDC25B | P30305 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405399 | 1.00 | MAPT (0.72) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL5175867 | 0.84 | MAPT (0.72) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL29728494 | 0.84 | MAPT (0.72) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL8663341 | 0.84 | MAPT (1.00) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL10391052 | 0.81 | P4HB (0.74) | MAPTKDM4ERECQLPOLBATM | |
| Plumbagin SCHEMBL29386213 | 0.81 | MAPT (1.00) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL30003609 | 0.81 | MAPT (0.64) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL29647651 | 0.81 | P4HB (0.74) | MAPTKDM4ERECQLPOLBATM | |
| SCHEMBL16879125 | 0.81 | MAPT (0.64) | MAPTKDM4ERECQLPOLBATM | |
| Plumbagin SCHEMBL34186 | 0.81 | MAPT (1.00) | MAPTKDM4ERECQLPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280402-B1 | TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING | BIOMENDICS LLC (US) | 2024-06-05 | — | — | EP | claimed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-20050183213-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one quinone direct dye, and process using this composition | L'OREAL S.A. (FR) | 2005-08-25 | — | — | US | claimed |
| EP-1559411-A1 | Composition for dying keratinic fibers containing an alcohol oxidase and a quinonic dye, and the method for use of the composition | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| US-5859066-A | APPLYING AN EFFECTIVE AMOUNT A 1,4-NAPHTHOQUINONE TO THE AFFECTED AREA OF THE SKIN | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-01-12 | — | — | US | claimed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | claimed |
| EP-0565417-A1 | Pigments consisting of an inorganic support and the reaction product of an indoline and a quinone derivative, their manufacturing process and their use in cosmetics | L'OREAL (FR) | 1993-10-13 | — | — | EP | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| US-5064442-A | HAIR DYES | L'OREAL (FR) | 1991-11-12 | — | — | US | claimed |
| US-4971596-A | COPPER, COBALT, IRON OR SILVER SALTS WITH QUINONE DYES | L'OREAL (FR) | 1990-11-20 | — | — | US | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| US-4832943-A | HYDROXYQUINONE, MESOTARTARALDEHYDE | L'OREAL (FR) | 1989-05-23 | — | — | US | claimed |
| JP-58157705-A | — | — | None | — | — | JP | disclosed |
| JP-S58157705-A | AGRICULTURAL AND HORTICULTURAL GERMICIDE | RIKAGAKU KENKYUSHO | 1983-09-19 | — | — | JP | disclosed |
| EP-0047323-A1 | 1,4-NAPHTHOQUINONE DERIVATIVES AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | MAPT 685/4885KDM4E 440/4885RECQL 1008/4885 |
| US-20050183213-A1 | Composition for dyeing keratin fibers, comprising at least one alcohol oxidase and at least one quinone direct dye, and process using this composition | KRT18, ADH5, ADH1A | MAPT 688/4885KDM4E 1088/4885RECQL 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.