SCHEMBL10993237

SCHEMBL10993237

FC(F)(F)c1ccc(Oc2c[c]ccc2)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.47
MEN1 O00255 1/20 0.44
TTR P02766 1/20 0.44
PPOX P50336 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR2A P28223 4/20 0.42
SLC6A4 P31645 4/20 0.42
KCNH2 Q12809 4/20 0.42
MRGPRX4 Q96LA9 5/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
STK39 Q9UEW8 1/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
ERBB3 P21860 1/20 0.39
ERBB4 Q15303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3110393 0.82 RAB9A (0.37) HTR2ASLC6A4KCNH2
SCHEMBL4867822 0.82 FFAR1 (0.54) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL9003844 0.82 FFAR1 (0.60) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL10538095 0.82 NPSR1 (0.57) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL27903177 0.81 SLC6A2 (0.47) HTR2ASLC6A4KCNH2MRGPRX4MAPT
SCHEMBL2751980 0.80 MRGPRX4 (0.50) FFAR1TTRSLC6A4MRGPRX4MAPT
SCHEMBL11095176 0.80 FFAR1 (0.65) FFAR1MEN1TTRPPOXKMT2A
SCHEMBL3484746 0.80 L3MBTL1 (0.39) FFAR1KMT2AHTR2ASLC6A4KCNH2
SCHEMBL3110346 0.78 RAB9A (0.34)
SCHEMBL11648951 0.78 FFAR1 (0.50) FFAR1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517010-A 2-Nitro-5(substituted-phenoxy) benzoyl derivatives as herbicides RHONE-POULENC INC. (US) 1985-05-14 US disclosed
EP-0069848-A2 Substituted phenoxyphenyl-azolylalkyl ethers, process for their preparation and their application as herbicides and as plant growth regulators BAYER AG (DE) 1983-01-19 EP disclosed
EP-0034883-A1 2-Nitro-5-(substituted-phenoxy) benzoyl derivatives as herbicides RHONE-POULENC INC. (US) 1981-09-02 EP disclosed