SCHEMBL1099549

SCHEMBL1099549

c1cc2c(nn1)-c1nccc3c1C2CCC3

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.34
ADRA1A P35348 2/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1B P35368 1/20 0.34
CYP2D6 P10635 2/20 0.31
HTR1A P08908 1/20 0.31
OPRM1 P35372 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1099603 0.82 ADRA2A (0.41) ADRA2AADRA1AADRA1DADRA1BCYP2D6
SCHEMBL1099582 0.78 ADRA2A (0.31) ADRA2AADRA1AADRA1DADRA1B
SCHEMBL1099599 0.75 ADRA1A (0.43) ADRA2AADRA1AADRA1DADRA1BCYP2D6
SCHEMBL1099175 0.66 CHRNB2 (0.32) ADRA2AADRA1AADRA1DADRA1BCHRNB2
SCHEMBL1099479 0.65 ADRA2A (0.37) ADRA2AADRA1AADRA1DADRA1BCYP2D6
SCHEMBL1102391 0.62
Ammonia Solution, Strong SCHEMBL8699361 0.61 GID4 (0.45) ADRA2AADRA1AADRA1DADRA1BCYP2D6
SCHEMBL19153315 0.59 CHRNB2 (0.36) CHRNB2CHRNA4
SCHEMBL19131863 0.56 CHRNB2 (0.33) CHRNB2CHRNA4
SCHEMBL968063 0.56 SIGMAR1 (0.43) ADRA2ACHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153276-B2 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-10 US disclosed
US-20100066237-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20090174326-A1 POLYMER MATERIAL AND POLYMER LIGHT-EMITTING DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-09 US disclosed