SCHEMBL1100153

SCHEMBL1100153

O=C(O)c1ccc2oc(=O)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 9/20 0.59
CA9 Q16790 9/20 0.59
MCL1 Q07820 3/20 0.59
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 6/20 0.55
PGR P06401 3/20 0.54
CA2 P00918 2/20 0.54
CA3 P07451 2/20 0.54
CA4 P22748 2/20 0.54
CA6 P23280 2/20 0.54
CA5A P35218 2/20 0.54
CA7 P43166 2/20 0.54
CA14 Q9ULX7 2/20 0.54
CA5B Q9Y2D0 2/20 0.54
KDM4E B2RXH2 4/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30388813 1.00 CA12 (0.59) CA12CA9MCL1MEN1KMT2A
Hydrochloric Acid SCHEMBL23294784 0.98 CA12 (0.58) CA12CA9MCL1MEN1KMT2A
SCHEMBL1099580 0.87 CA9 (0.58) CA12CA9MCL1MEN1KMT2A
SCHEMBL15842681 0.84 CA9 (0.59) CA12CA9MCL1MEN1KMT2A
SCHEMBL23294766 0.84 CA12 (0.58) CA12CA9MCL1MEN1KMT2A
SCHEMBL19691118 0.84 CA12 (0.58) CA12CA9MCL1MEN1KMT2A
SCHEMBL26054575 0.80 CA9 (0.53) CA12CA9MCL1MEN1KMT2A
SCHEMBL15842312 0.80 CA9 (0.53) CA12CA9MCL1MEN1KMT2A
SCHEMBL15842575 0.80 CYP2A6 (0.57) CA12CA9MCL1MEN1KMT2A
SCHEMBL15842574 0.80 PTPN1 (0.56) CA12CA9MCL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033655-A1 CHIRAL SUPRAMOLECULAR HIGH-ORDER STRUCTURE BASED ON CO-ASSEMBLY OF STAR-SHAPED BLOCK COPOLYMER AND CHIRAL ADDITIVE AND MANUFACTURING METHOD THEREOF 이화여자대학교 산학협력단 2025-02-13 WO claimed
CN-119230977-A Zinc ion battery electrolyte and preparation method and application thereof 陕西延长石油售电有限公司 2024-12-31 CN claimed
CN-118558143-B Method for preparing nanofiltration membrane based on pyrone acidic molecular additive regulation 东华理工大学 2024-12-20 CN claimed
CN-118558143-A Method for preparing nanofiltration membrane based on pyrone acidic molecular additive regulation 东华理工大学 2024-08-30 CN claimed
EP-2295053-B1 Novel 2H-chromen-2-one-3-carboxamides for medical uses INST MATERIA MEDICA CAMS (CN) 2016-10-19 EP claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-8338401-B2 Coumarin-amide derivatives and its preparation, said drug composition and its use INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2012-12-25 US claimed
EP-2295053-A1 Novel 2H-chromen-2-one-3-carboxamides for medical uses THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2011-03-16 EP claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-100488504-C Coumarin amide derivative, its preparation method, its medicinal composition and application INST MATERIA MEDICA CAMS (CN) 2009-05-20 CN claimed
US-20060148834-A1 Novel coumarin-amide derivatives and its preparation, said drug composition and its use INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2006-07-06 US claimed
EP-1570846-A1 THE NOVEL COUMARIN-AMIDE DERIVATIVES AND ITS PREPARATION, SAID DRUG COMPOSITION AND ITS USE THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2005-09-07 EP claimed
EP-3710428-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-25 EP disclosed
EP-4683951-A2 METHOD OF FUNCTIONALIZATION OF A BIOPOLYMER AND METHOD OF CROSS-LINKING THEREOF Polbionica Spolka Akcyjna (PL) 2026-01-28 EP disclosed
CN-119709024-A Photo-curing adhesive, preparation method thereof, display screen and electronic equipment 北京小米移动软件有限公司 2025-03-28 CN disclosed
EP-1988085-A1 PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS TOYAMA CHEMICAL CO., LTD. (JP) 2008-11-05 EP disclosed
EP-1988085-A1 PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS TOYAMA CHEMICAL CO., LTD. (JP) 2008-11-05 EP disclosed
US-20060148834-A1 Novel coumarin-amide derivatives and its preparation, said drug composition and its use INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2006-07-06 US disclosed
EP-1570846-A1 THE NOVEL COUMARIN-AMIDE DERIVATIVES AND ITS PREPARATION, SAID DRUG COMPOSITION AND ITS USE THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2005-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148834-A1 Novel coumarin-amide derivatives and its preparation, said drug composition and its use INSR, GLS, INSRR CA12 3153/4885CA9 863/4885MCL1 779/4885
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 CA12 15/4885CA9 120/4885MCL1 3462/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA CA12 403/4885CA9 526/4885MCL1 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.