Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180902 | 0.76 | TGM2 (0.40) | TSHRTGM2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL9181403 | 0.72 | TSHR (0.48) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL717181 | 0.72 | TSHR (0.48) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL49520 | 0.72 | TSHR (0.48) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL6910659 | 0.69 | TSHR (0.43) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL1371114 | 0.69 | TSHR (0.43) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL7691374 | 0.68 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1HSD17B10CTSD | |
| SCHEMBL725270 | 0.68 | ESR1 (0.35) | TSHRALDH1A1MAPT | |
| SCHEMBL824771 | 0.67 | ALDH1A1 (0.53) | TGM2ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11852672 | 0.67 | TSHR (0.42) | TSHRALDH1A1TDP1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555420-A | DIFUNCTIONAL NITROGEN-CONTAINING SILANE CURING AGENTS; LOW MODULUS ENCAPPED POLYSILOXANES | GENERAL ELECTRIC COMPANY (US) | 1985-11-26 | — | — | US | disclosed |