SCHEMBL1101043

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1100051	0.93	ALOX5 (0.45)	ATP4AATP4BALOX5PSEN1GCGR
	SCHEMBL1100447	0.92	SMPD1 (0.40)	ATP4AATP4BALOX5PSEN1SMPD1
	Bicarbonate SCHEMBL16224031	0.86	ATP4A (0.46)	ATP4AATP4BALOX5PSEN1GCGR
	SCHEMBL1100928	0.85	FFAR1 (0.42)	ATP4AATP4BALOX5PSEN1GCGR
	SCHEMBL1745385	0.82	PPARD (0.55)	ATP4AATP4BALOX5PSEN1GCGR
	Bicarbonate SCHEMBL16223879	0.78	ALOX5 (0.41)	ATP4AATP4BALOX5PSEN1GCGR
	SCHEMBL1100877	0.78	GCGR (0.51)	ATP4AATP4BGCGRGIPRALDH1A1
	SCHEMBL3917963	0.77	PPARD (0.49)	ATP4AATP4BALOX5PSEN1GCGR
	SCHEMBL3920620	0.76	PPARD (0.45)	ATP4AATP4BALOX5PSEN1SMPD1
	SCHEMBL3922019	0.75	ALOX5 (0.47)	ATP4AATP4BALOX5PSEN1GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.